Download Clinical Asthma: Theory and Practice by Jonathan A. Bernstein, Mark L. Levy PDF

By Jonathan A. Bernstein, Mark L. Levy

Huge, immense growth in bronchial asthma learn has been made long ago 50 years, together with a better figuring out of its complicated pathogenesis and new and more desirable remedies. as a result, the medical literature has grown large and will be tough to combine. With contributions from a extraordinary panel of world-renowned authors, medical bronchial asthma: thought and perform provides a accomplished examine of either the Read more...

Show description

Read Online or Download Clinical Asthma: Theory and Practice PDF

Best pulmonary & thoracic medicine books

Cilia and Mucus: From Development to Respiratory Defense

This publication information advances in learn relating to cilia, mucus, and mucociliary clearance, studying adjustments in mucus expression and goblet mobilephone metaplasia, and assessing the facility of the mucociliary method to answer abnormalities. acknowledges that cilia and dynein fingers play pivotal roles in constructing mammalian embryos!

Endothelium : molecular aspects of metabolic disorders

The functionality and lifestyles span of endothelial cells have a wide impression upon the standard and expectancy of an individual's existence. in the course of low perfusion, the difference of other cells to hypoxia precipitate the competitive development of ailments. even if the medical experiences have convincingly proven that endothelial disorder happens every time the organic capabilities or bioavailability of nitric oxide are impaired, in a lot of these situations, the position of endothelial cell-destructive method cross-talk is but poorly understood.

The Breathless Heart: Apneas in Heart Failure

This booklet systematically makes a speciality of principal sleep apneas, studying their courting in particular with middle failure and discussing fresh study effects and rising therapy concepts in response to suggestions modulation. the outlet chapters current ancient history info on Cheyne-Stokes respiratory (CSR), make clear terminology, and clarify the mechanics and chemistry of breathing.

Extra resources for Clinical Asthma: Theory and Practice

Example text

Interactions between genes and environment in the development of asthma. Allergy 2001;56:279–286. 38. Van den Oord RA, Sheikh A. Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: Systematic review and meta-analysis. BMJ 2009;339:b2433. Moffatt MF, Kabesch M, Liang L. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007;448:470–473. Srivastava P, Helms PJ, Stewart D, et al. Association of CCR5Delta32 with reduced risk of childhood but not adult asthma.

Eosinophil’s role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airways. Am J Respir Crit Care Med 2003;176:199–204. 22. Nair P, Pizzichini MM, Kjarsgaard M, et al. Mepolizumab for prednisolone-dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985–993. Haldar P, Brightling CE, Hargadon B, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973–984. 24. Holgate ST. Pathophysiology of asthma: What has our current understanding taught us about new therapeutic approaches?

Nature 2007;448:470–473. Srivastava P, Helms PJ, Stewart D, et al. Association of CCR5Delta32 with reduced risk of childhood but not adult asthma. Thorax 2003;58:222–226. Van Eerdewegh P, Little RD, Dupuis J, et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2002;418:426–430. 42. Hersh CP, Raby BA, Soto-Quiros ME, et al. Comprehensive testing of positionally cloned asthma genes in two populations. Am J Respir Crit Care Med 2007;176:849–857. 43. Kim J-H, Ellwood PE, Asher MI.

Download PDF sample

Rated 4.36 of 5 – based on 9 votes