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By Johny A. Verschakelen, Walter De Wever

The second one version of Connective Tissue and Its Heritable issues: Molecular, Genetic, and clinical elements is the definitive reference textual content in its box, with over forty% extra pages at the nature, analysis, and therapy of illness than its predecessor.  accumulating new study on issues distinct within the first variation in addition to on these formerly excluded, editors Peter Royce and Beat Steinmann give you the most recent scientific and clinical details for clinical experts treating affected individuals.  beneficial properties of this revised and up-to-date quantity contain special reports of the medical prognosis, mode of inheritance, threat of recurrence, and prenatal prognosis of every inherited connective tissue disease; an intensive description of the morphology of connective tissues; a totally up-to-date and revised part at the biology of the extracellular matrix; and the addition of syndromes reminiscent of craniosyntosis, and issues of sulfate metabolism.

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Extra resources for Computed Tomography of the Lung A Pattern Approach

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4 Linear Pattern The nodular pattern (Fig. 9) is characterised by the presence of multiple nodular opacities with a maximum diameter of 3 cm. A nodule with a diameter less than 1 cm can be defined as a small nodule, whereas a nodule larger than 1 cm is often called a large nodule (Grenier et al. 1991). The term “micronodule” usually refers to nodules no larger than 7 mm in diameter (Austin et al. 1996). The CT assessment of the nodular pattern is based on: ¼ Their size (small or large) ¼ Their appearance (well-defined or ill-defined) ¼ Their attenuation (soft tissue or ground-glass density) ¼ Their distribution [(peri)lymphatic, centrilobular, at random] The linear pattern is characterised by the presence of multiple lines.

Ground-glass opacity is associated with linear opacities, creating a crazy-paving pattern b Fig. 9a,b. Usual interstitial pneumonia in a patient with systemic sclerosis. a The dominant pattern is ground-glass opacity, which is located in the dorsal and basal subpleural region of both lungs, suggesting active lung disease. However, at the basal slice (b), there is some irregular interstitial thickening together with some bronchial distortion (arrow), suggesting the presence of fibrosis in that part of the lung Fig.

J Comput Assist Tomogr 17:352–357 Bourgouin P, Cousineau G, Lemire P et al (1987) Differentiation of radiation-induced fibrosis from recurrent pulmonary neoplasm by CT. Can Assoc Radiol J 38:23–26 Brauner MW, Grenier P, Mompoint D et al (1989) Pulmonary sarcoidosis: evaluation with high-resolution CT. Radiology 172:467–471 Brauner MW, Lenoir S, Grenier P et al (1992) Pulmonary sarcoidosis: CT assessment of lesion reversibility. Radiology 182:349–354 Cheon JE, Lee KS, Jung GS et al (1996) Acute eosinophilic pneumonia: radiographic and CT fi ndings in six patients.

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