By K. Sandhoff, P. Leinekugel (auth.), J. A. F. Op den Kamp (eds.)
Membrane proteins, lipids and their glycosylated derivatives are mentioned either with appreciate to their biosynthesis in addition to concerning their mutual interplay and meeting into practical membranes. subject matters disguise a wide number of structures and cells: research on virus membranes in addition to professional- and eukaryotic cells are included.
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Extra info for Dynamics and Biogenesis of Membranes
J BioI Chern 262:4297 -4302. Magee AI, Courtneidge SA (1985) Two classes of fatty acid acylated proteins exist in eukaryotic cells. EMBO J 2:1137-1144. Magee AI, Gutierrez L, McKay I, Marshall C, Hall A (1987) Dynamic fatty acylation of p21 Nras. EMBO J 6:3353-3357. Malvoisin E, Wild F, Zwingelstein G (1987) 12-0-tetradecan-oyl phorbol 13-acetate stimulates the myristylation of an approximately 82 kDa protein in HL-60 cells. FEBS Lett 215:175178. McIlhinney RAJ, Pelley SJ, Chadwick JK, Cowley GP (1985) Studies on the attachment of myristic and palmitic acid to cell proteins in human squamous carcinoma cell lines: evidence for two pathways.
The structures of the aggregates in groups 1-3 are well established (cf Fig. 1). 45 A B c Figure 1. Structure of the most common anisotropic liquid crystalline phases that membrane lipids can form. (A) Normal hexagonal (Hr) phase; (B) lamellar (La) phase; and (C) inverted hexagonal (Hn) phase. , 1984. The positions in the phase diagram of the various phases occurring in a lipid-water system often give very helpful information about the physicochemical properties and, in particular for the many possible different cubic phases, about the aggregate structure building up the phases.
Nature 326:309-312. Grand RJA, Smith KJU, Gallimore PH (1987) Purification and characterization of the protein encoded by the activated human N-ras gene and its membrane localization. Oncogene 1:305-314. Kamps MP, Buss JE, Sefton BM (1985) Mutation of NHa-terminal glycine of p60 src prevents both myristoylation and morphological transformatIOn. Proc Natl Acad Sci USA 82:46254628. Khandwala AS, Casper CB (1971) The fatty acid composition of individual phospholipids from rat liver nuclear membrane and nuclei.