Download Ethylenimine and Other Aziridines. Chemistry and by O. C. Dermer PDF

By O. C. Dermer

Show description

Read or Download Ethylenimine and Other Aziridines. Chemistry and Applications PDF

Best chemical books

Chemical Mutagens: Environmental Effects on Biological Systems

Chemical Mutagens: Environmental results on organic platforms brings jointly correct proof approximately artificial and of course happening mutagenic chemical substances. equipped into components, this e-book starts off with an easy dialogue at the sleek techniques of the gene on the molecular and biochemical degrees. the 1st half additionally seems to be into the different sorts of mutations and the way they shape, in addition to the organic platforms used for his or her detection.

Mesoscale modeling in chemical engineering. / Part II

Mesoscale Modeling in Chemical Engineering, a quantity within the Advances in Chemical Engineering sequence offers the reader with own perspectives of professionals within the box. topics lined aren't restricted to the classical chemical engineering disciplines, with contributions connecting chemical engineering to similar medical fields, therefore supplying new principles for added suggestion.

Extra resources for Ethylenimine and Other Aziridines. Chemistry and Applications

Sample text

As th e free epimine . TH F = tetrahydrofuran . N o benzyliden e grou p present . Of th e benzylidenebis(aziridine) . Along with 25 % of th e oxazoline . Oxazolin e also formed . In othe r cases, not cited here , th e â-hexos e derivativ e gave only th e oxazoline , etc. No benzyliden e grou p present , bu t a 5-mesyl was. * Th e 5-Ms grou p was displace d by th e 5-Bz grou p in th e product . No benzyliden e grou p present , bu t a 5-azid o grou p was. Th e produc t was isolate d as th e dibenzoy l derivative .

9 ÷ 1 0 s e c . b c 5 1 d e f - 5 - 5 -1 - 5 -1 -1 9 h - 5 -1 + In contrast, B z N H C H M e C H P h S M e I " gives only the oxazoline (3465). 1]octan-e«ifo-7-ol tosylate are best explained by postulating the acylaziridinium ion 3 8 as an intermediate (1792). 2 CH P h 2 Desire for possible antitumor drugs and intermediates for synthesis of various amino sugars has motivated related research. 1 eq. 1JV NaOM e or NaOH , resp . 6N Mixed ales. p. p. p. p. p. , resp . p. p. p. 100 25 (°Q Temp . Reactio n condition s PREPARATIO N OF 2,3-EPIMIN O SUGAR DERIVATIVE S Tabl e 1-IX c c c c 32 38 56 * 49* 78 / 61 68-73 — 60 Few 120 45 30 120 60 — 88-90 — 65 29 72 53 53 76 85 Yield (% ) — 4-5 90 30 180 20 1080 10 Few Tim e (min.

0 NC H ) 6 2 4 6 4 2-(p-0 NC H CO)-3-P h 1,3-Me -2-(^-PhC H CO ) 2,3-Bz -l-M e 2 6 4 2 6 4 2 l-Me-3-Ph-2-(^-MeC H CO ) 6 4 2,3-Bza-l-E t 1-c-QH i -2-(;7-PhC H CO ) 2-Bz-l-c-C H -3-P h 1 6 6 4 n 2-Bz-l-c-C H -3-(/7-MeOC H ) 2-Bz-l-c-C H -3-(/7-0 NC H ) 2-Bz-l-c-QH ! 6 43 50 40 High — 80 — 78 46 50-54 — 97-100 — 89 60-90 » 68 65 43 INTRAMOLECULA R DISPLACEMEN T BY TH E AMIN O GROU P Tabl e 1-V—continue d Aziridin e made , or substituent s therei n Method " % Yield" Reference s Aziridines Containing No Functional Groups—continued 2-Bz-l-PhCH -3-P h 2 2-Bz-l-PhCH -3-(m-0 NC H ) l-c-C H -3-Me-2-(p-PhC H CO ) l-c-C H !

Download PDF sample

Rated 4.63 of 5 – based on 15 votes