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By Paola Antonini (auth.), Professor Cankat Tulunay, Professor Michael Orme (eds.)

“European Collaboration: in the direction of Drug improvement and Rational Drug treatment “ is the name of the sixth Congress of the ecu organization for scientific Pharmacology and Therapeutics ( EACPT )being held in Istanbul,Turkey from June twenty fourth -28th 2003. Istanbul has been selected because the venue for this congress as a distinct urban bridging continents and bringing jointly scientists from loads of nations. This quantity has been edited by means of Prof Cankat Tulunay ( the President of the Congress ) and Prof Michael Orme ( co-ordinator of the medical Committee and Hon. Secretary of EACPT. the quantity comprises info of the 21 symposia and three workshops which are occurring in Istanbul including the abstracts from the greater than four hundred submitted and being offered in Istanbul. The organisers desire that you're going to take pleasure in either the medical and cultural elements of this Congress. desk of contents Abstracts of lectures 1 desk of abstracts 39 Abstracts sixty nine Abstracts of lectures 23 June 2003 complete Day path certainly you will need to rigidity that this approach in advent to the method of scientific Trials a continuum, with worthwhile details coming from assorted departments contributing day through Paola Antonini day to the ultimate product profile. Key parts of Pre- clinical Affairs Director, Merck Sharp & Dohme medical improvement are Pharmacology, Toxicol- Italy ogy, Pharmacokinetics and Chemistry and Ph- macy.

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Additional resources for European Collaboration: Towards Drug Developement and Rational Drug Therapy: Proceedings of the Sixth Congress of the European Association for Clinical Pharmacology and Therapeutics Istanbul, June 24 – 28, 2003

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Trombert B. , Rojas M. , Loizzo A. , Radenkovic M. , Grbovic L. Cardiovascular pharmacology and therapeutics P -15 Randomised Non-blinded Two-fold Cross-over Study to Assess the Relative Bioavailability of the ASA Dry Granules 500 mg Given with and without Water to 24 Healthy Male Subjects Latta G, Voith B, Nagelschmitz J Pharmacokinetics 41 25. , Rane A. , Müller M. , ,Aulagner G. , Hazar A. Pharmacokinetics P - 17 Positron Emission Tomography for the Description of Target Tissue Pharmacokinetics of [18F] Fluorine-labelled Ciprofloxacin.

Setting: A 34- bed medical ward at the Hadassah University Hospital, Jerusalem, Israel. Measurements: Analysis of computerized laboratory data according to defined automated signals (AS) generated from the laboratory as potential indicators of ADR. Chart review for ADR and whether these were were recognized by the staff physicians. Results: In one-quater to one-third of the admissions ADR were present. Duration of hospitalization increased by 50% in the ADR-positive admissions. About 60% of the ADR were identified by AS.

Walley T. Pharmacoepidemiology P - 61 Some Degradation Pathways Affecting the Biological Activity of IFN Alpha 2b, Interleukin 2 and Epidermal Growth Factor Ruiz L. , Kalyoncu N. , Kalyoncu N. , Ciriello J. H. Pain 44 Drug utilization P - 62 The Influence of Some Formulation Factors on the Protein Stability Ruiz L. , Potogija N. Pharmacokinetics P - 64 Development of Formulations of Interleukin 2 with a Long-Term Stability Reyes N. Drug utilization P - 65 Development of New Albumin-Free Formulations of Interferon Alpha 2b for Clinical Purposes Hardy E.

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