Download Hepatitis C Viruses by Seng-Lai Tan PDF

By Seng-Lai Tan

Hepatitis C is famous as the most vital new illnesses afflicting guy. the invention, prognosis and preliminary remedies of hepatitis C virus (HCV) an infection are all excellent examples of the expanding impression molecular biology is at the moment having on ailment administration through the globe. either the depth and breadth of HCV study are transforming into at a striking velocity and intriguing new discoveries have gotten virtually standard. This e-book discusses the latest elements of HCV an infection, replication and molecular biology. The authors assessment the present nation of growth in HCV molecular biology and speak about the questions which are at present dealing with molecular investigators. The chapters supply in-depth studies of the main severe parts of HCV molecular learn at the present time.

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2005). Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication. J Virol 79, 380-392. , and Bartenschlager, R. (2001). Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication. J Virol 75, 12047-12057. , and Hotta, H. (1996). Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virus. Biochem Biophys Res Commun 229, 825-831. , Wands, J. , and Li, J. (2005). Hepatitis C virus core protein stimulates hepatocyte growth: correlation with upregulation of wnt-1 expression.

Hepatology 39, 5-19. Petit, J. , Bour, J. , Brun, J. , and Hillon, P. (2003). Hepatitis C virus-associated hypobetalipoproteinemia is correlated with plasma viral load, steatosis, and liver fibrosis. Am J Gastroenterol 98, 1150-1154. , et al. (2000). Structure-function analysis of hepatitis C virus envelope-CD81 binding. J Virol 74, 4824-4830. , Raney, K. , and McCarthy, J. E. (2002). Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.

And Klumpp, K. (2005). Inhibition of native hepatitis C virus replicase by nucleotide and non-nucleoside inhibitors. Virology 332, 8-15. , and Budkowska, A. (2001). Nonenveloped nucleocapsids of hepatitis C virus in the serum of infected patients. J Virol 75, 8240-8250. , Lavergne, J. , Teillaud, J. , and Budkowska, A. (2004). Fcgamma receptor-like activity of hepatitis C virus core protein. J Biol Chem 279, 2430-2437. , Majeau, J. , and Leclerc, D. (2004). The N-terminal half of the core protein of hepatitis C virus is sufficient for nucleocapsid formation.

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