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By P. Roy Vagelos

P. Roy Vagelos grew up through the melancholy as a wise-cracking son of Greek immigrants. He left his family's small eating place to turn into a physician and went directly to grasp 3 professions and develop into the manager govt Officer of the multinational pharmaceutical substantial, Merck & Co. medication, technology, and Merck follows Vangelos' lifestyles from adolescence to retirement, from his educational years on the college of Pennsylvania, Columbia University's scientific college, and Massachusetts normal sanatorium via his specialist profession on the nationwide Institute of future health, Washington college, and Merck. all through, Vagelos by no means misplaced contact together with his kin values, his severe wish to aid others, and his religion within the partnership precept and the contest that makes it paintings. P. Roy Vagelos and Louis Galambos supply an strange standpoint on operating in 3 prime professions: drugs, technology, and enterprise. They take readers contained in the laboratory and boardroom of 1 of America's huge firms, studying the blunders and the strategies of Merck. P. Roy Vagelos, M.D. served as CEO of Merck & Co., Inc. from 1985 to 1994. sooner than assuming tasks in enterprise management, he had gained medical attractiveness as an expert on lipids and enzymes and as a learn supervisor. the writer of greater than a hundred clinical papers, Vagelos has been elected to the yankee Academy of Arts and Sciences, the nationwide Academy of Sciences and the yankee Philosophical Society. Louis Galambos has written commonly on U.S. business-government kinfolk, on fiscal elements of recent institutional advancements and at the upward thrust of the bureaucratic kingdom. A professor at Johns Hopkins college, Professor Galambos is the writer of a number of books, together with every time, wherever (Cambridge, 2002).

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Occasionally, she arranged for ∗ The woman intern was Kathy Spreng, who married Tom Waldman, one year behind us as an MGH intern. Kathy went on to have a productive medical career, and Tom became an important immunologist at the National Institutes of Health. 15:0 P1: IKB CB607-01 32 CB607-Vagelow-v1 December 8, 2004 The Making of a Physician us to attend the Boston Symphony on my nights off (where, alas, I usually slept through much of the concert). During that tense year, she and I were able to see each other about every four months, and by this time, we had both passed muster with our respective families.

My mother ran the kitchen, Herodotus was out front making sandwiches and handling the cash register, and my sister Joan waited on tables. Even my grandmother was occasionally pressed into service peeling potatoes – a task she clearly felt was beneath her. By the time Helen turned ten, she too was assigned regular hours at Estelle’s. I split duty between the kitchen, where I peeled potatoes and washed dishes, and the fountain, where I was a soda jerk. My parents spent long hours there, and the family had dinner together at Estelle’s every night except Sunday, when the place was closed.

The only positive result was to make medical school and a career in medicine look even more attractive. During the following years at P&S, I became deeply engaged in mastering medicine. I became especially interested in cardiovascular disease and began to contemplate a career in clinical cardiology, treating patients who had suffered heart attacks or strokes. In the back of my mind, however, was the idea that biochemistry, or the chemistry of living things, might provide the basis for understanding much of cardiology and of the rest of medicine.

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